Cytomegalovirus infection

Cytomegalovirus infection

Cytomegalovirus infection	Cytomegalovirus antibodies (IgG and IgM). IgG antibodies will be present in a high proportion of adults from previous, often asymptomatic, infection. Seroconversion, with a fourfold increase in titre, supports the diagnosis. The presence of specific (CMV) IgM antibody may indicate recent infection, but levels may remain increased for long periods and false positives also occur, making the test less useful than IgM detection in other infections. Virus detection, culture of urine, buffy coat or tissue may be required. Histological identification of virus and its cytopathic effects in infected cells (biopsy of eg lung, liver, colon, kidney) is a more specific test for infection than is demonstration of excretion of virus.
Fever
Cervical lymphadenopathy
Hepatitis
Congenital infection
Post-transfusion
Immunodeficiency esp	Cytomegalovirus detection .
Post-transplantation AIDS
Cytotoxic drug therapy
Immunosuppressive therapy